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Treatment of mice with 2APB 2APB (Sigma, D9754) was made fresh for each experiment (dissolved in DMSO at 100 mg/ml as the stock)
Take a pea-sized amount of the cream on your fingertips
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Jan 5, 2026 Bone, despite being highly vascularized tissue, requires precise orchestration of inflammatory phase (hematoma formation, cytokine release), repair phase (callus formation, cartilaginous bridge), and remodeling phase (ossification, mechanical adaptation) spanning weeks to months
